
01 March 2023
Hydroxycarbamide 100 mg/ml oral solution (Xromi®): Changes to the oral syringes co-packaged with Xromi®
Dear Patient/Carer,
We are writing to you as you have been prescribed Xromi®, a treatment for preventing complications of Sickle Cell Disease in patients over 2 years of age.
As you are aware, the current Xromi® product packaging includes a small 3 ml syringe (with red plunger) and a large 12 ml syringe (with white plunger).
Due to global supply issues, it has been necessary to make changes to the oral syringes we provide. The new packaging contains a small 3 ml syringe (with violet plunger) and a large 10 ml syringe (with violet plunger). In addition to the change in colours, the size and markings on the larger syringe have also changed. This will not impact the safety or effectiveness of the medicine.


For future prescriptions, your doctor may need to adjust your dose slightly. If you have any concerns, please speak to your doctor.
The product information has been updated to describe these changes. Your doctor or pharmacist can advise you on which syringe to use (3 ml or 10 ml) to ensure that the correct volume is administered.
If you have any other questions about Xromi®, please call the information line provided below:
Medical Information Direct line: 08707 120 655
Yours sincerely,
Janet Box
Head of Quality Assurance
Nova Laboratories Ltd